Description Isotretinoin belongs to a class of drugs called retinoids, which are synthetic derivatives of vitamin A. These drugs are used to treat severe acne and other skin conditions. Topical isotretinoin has been shown to be effective as a treatment in combination with other medications for oral lichen planus. Because isotretinoin is derived from vitamin A, users of this drug should be careful to avoid vitamin A supplements, as this can cause dangerous side effects.
Original uses (on-label) Severe acne unresponsive to conventional therapy.
Newly discovered uses (off-label) Also, patients can order isotretinoin online to treat leukoplakia, oral lichen planus, prevention of recurrence of oral cancer.
Potential side effects Increased heart rate, headache, visual disturbances, malaise, nervousness, dry lips, dry skin, hair abnormalities, skin peeling, increased susceptibility of sunburn, itching, nausea, fatigue, suicidal ideation.
Cautions
Drug interactions Corticosteroids, phenytoin, tetracycline, carbamazepine.
Food interactions Take with food
Herbal interactions Dong quai, St. John's wort, and additional vitamin A supplements.
Pregnancy and breast-feeding cautions FDA Pregnancy Risk Category X. Excretion in breast milk is unknown. Use during breast-feeding is not recommended.

Do not buy Accutane if you are pregnant or may become pregnant while undergoing therapy. The chances are extremely high that the infant will be deformed if Accutane is used during pregnancy, or if pregnancy occurs while taking generic Accutane, in any amount, even for short periods of time.
Special information This drug has a black box warning describing the known teratogenic effects when taken during pregnancy. In addition, it describes the restricted dispensing program that requires signed patient consent and counseling along with negative pregnancy tests prior to the initiation of therapy. Additional information is also provided regarding the risk of suicidal ideation. Read the complete patient brochure and discuss these risks with your doctor.