Minocycline is used to treat a number of bacterial infections. For Legionnaire's disease, certain antibiotics, such as minocycline, are recommended since they have high concentrations and are active against Legionella bacteria.
Therapy with antibiotics, in general, should last for two weeks in mild disease, and three weeks in severe disease and in persons with decreased immunity. Side effects associated with generic Minocin include upset stomach, diarrhea, dizziness, unsteadiness, drowsiness, headache, and vomiting, among others.
Original uses (on-label)
Treatment of various bacterial infections, acne.
Newly discovered uses (off-label)
Also, patients can order minocycline to treat legionnaire's disease, Lyme disease, mycoplasma pneumonia, nocardiosis, rheumatoid arthritis, rosacea.
Potential side effects
Generic Minocycline side effects include dizziness, upset stomach, photosensitivity reaction (see cautions), itching, discoloration of teeth and enamel (young children), nausea, diarrhea, abdominal cramps, liver toxicity.
Patients who buy Minocycline online need to be aware of a few basic precautions to avoid health problems.
- It should not be used in young children (under 8 years of age).
- If used during tooth development may cause permanent discoloration of the tooth enamel.
- May retard skeletal development and bone growth with greatest risk for children less than four years and those receiving high doses.
- Not for use during pregnancy.
- Notify your doctor if persistent diarrhea develops.
- May cause photosensitivity reactions (skin reaction related to sun exposure). Wear sunscreen and protective clothing during sun exposure.
- Chronic use may result in superinfection.
- Dosages may be reduced in kidney impairment.
- Before buying Minocycline, you must inform your doctor if you have a history of allergies to other antibiotics in this class or if you have liver or kidney problems.
- Do not use outdated tetracycline products.
Warfarin, certain antibiotics (check with doctor or pharmacist), methoxyflurane, oral contraceptives, isotretinoin
Pregnancy and breast-feeding cautions
FDA Pregnancy Risk Category D. Excreted in breast milk. Do not use during breast-feeding.
Legionnaires disease treatment
You can order Minocycline for treatment of Legionnaires disease. In a study conducted at the Department of Health in Pennsylvania, five antibiotics, including Minocin, were tested in guinea pigs with Legionnaire's disease. In this study, the most effective antibiotic was Minocin; use of this drug resulted in a 50% survival rate in infected guinea pigs. The other antibiotics, rifampin, amikacin, tobramycin, and gentamycin, were less effective.
In this study, surviving guinea pigs remained healthy and were able to produce antibodies (molecules in body fluids that destroy or neutralize bacteria and toxins) to the Legionella bacteria. In another laboratory study, minocycline was found to be the most effective drug in guinea pigs infected with Legionnaire's disease. Minocin was as effective as doxycycline (an antibiotic) in blocking the growth of Legionella bacteria, and prolonged the animals' survival. Overall, this drug is recognized as having antibiotic activity against this type of bacteria.
Rheumatoid Arthritis treatment
Minocycline is sometimes prescribed for patients with symptoms of mild rheumatoid arthritis.
It may take two to three months improvement begins and a year before maximum benefits occurs.
Arthritis & Rheumatism reported on a study in 46 patients in their first year of RA who received either minocycline or placebo. After six months, those on Minocin significantly improved compared to those on placebo.
In a follow-up study of 38 of these patients for an average of four years, those who had received minocycline initially were most likely to be in remission (40% vs. 17%) and less likely to require a disease-modifying antirheumatic drug (50% vs. 90%).
Based on these results, researchers strongly suggest that minocycline in early RA is beneficial.
A trial, also published in Arthritis & Rheumatism, involved 219 people with mild-to-moderate RA who received placebo or minocycline for 48 weeks.
Minocin patients experienced a greater than 50% improvement in joint swelling and tenderness, and all improvements were significant compared to the placebo group.
What is Minocycline?
This drug inhibits the production of bacterial proteins by hindering essential cell function.
Brands & Classes
Tablets Oral 100 mg
PO 200 mg, then 100 mg q12h or 50 mg q6h, not to exceed 400 mg/24h.
Gonorrhea (not drug of choice): PO 200 mg, then 100 mg q12h for 4 days.
Chlamydia trachomatis, Ureaplasma urealyticum: PO 100 mg bid for 7 days.
Syphilis (PCN allergic patients): PO 200 mg, then 100 mg q12h for 10-15 days.
Acne: PO 50 mg 1-3 times/day.
Skin granulomas from M. marinum: PO 100 mg bid for 6-8 week.
CHILD > 8yr
PO 4 mg/kg then 2 mg/kg every 12 hours.