Clopidogrel belongs to the class of drugs called antiplatelet drugs.
This class of medications that reduce the ability of platelets (specialized blood cells) to stick together, which occurs normally as part of the blood-clotting process.
Antiplatelet drugs are used to prevent the formation of blood clots in arteries, when anticoagulants are ineffective.
Plavix used to prevent strokes or heart attacks occurring in people at risk, particularly in those who have had a previous stroke or heart attack.
Original uses (on-label)
Reduction of atherosclerotic
events (myocardial infarction
, and vascular death) in patients with atherosclerosis documented by recent stroke, myocardial infarction, or established peripheral arterial disease; prevention of thrombosis following intracoronary stent placement; acute coronary syndromes.
Newly discovered uses (off-label)
Mechanism of action
Selectively and irreversibly inhibits ADP-induced platelet aggregation by inhibiting the binding of ADP to its receptors on platelets, thereby affecting ADP-dependent activation of the glycoprotein IIb / IIIa complex, the major site of platelet-fibrinogen binding.
Potential side effects
Bleeding from the stomach, intestines, or elsewhere can occur. Other side effects may include nausea, vomiting, abdominal discomfort, constipation, diarrhoea, headache, dizziness, and rashes. Contact your healthcare provider or pharmacist if you experience any other effects not listed here.
- If you have a history of gastrointestinal bleeding or a history of clotting disorders or ulcers, you should not use this medication.
- It is not recommended for people with severe angina or for those who have had coronary-artery surgery.
- It should be used with caution in people with liver or kidney disease.
Before buying Plavix, you will need to closely monitor your dosage and condition if you are also taking the following medications: warfarin, heparin, ibuprofen or naproxen (NSAIDs), phenytoin, tamoxifen, tolbutamide, torsemide, and fluvastatin as certain medicines or medical conditions may interact with this medicine.
Warfarin should not be used with clopidogrel. Anticoagulants: their effects are enhanced by Plavix. NSAIDS (including aspirin): may increase the risk of gastrointestinal bleeding.
Take without regard to meals.
Pregnancy and breast-feeding cautions
Pregnancy category B. This means that it is not expected to harm an unborn baby. Do not take Plavix without first talking to your doctor if you are pregnant.
Buy Plavix online
Where can I buy Clopidogrel?
Clopidogrel is a prescription drug that comes in 75 mg tablets.
It is available on prescription only as tablets for oral use, but the online pharmacy, will sell Clopidogrel without prescription.
You may be able to order Plavix from them online and save the local pharmacy markup.
Should probably replace ticlopidine as an aspirin alternative.
Inform clinician of signs and symptoms of bleeding, prior to surgery, dental work; inform clinician of sore throat, fever, etc. (consider neutropenia).
What is Plavix?
Clopidogrel helps to prevent blood clots.
Brands & Classes
Plavix, Caplor, Clavix
Tablets - Oral 75 mg.
PO 75 mg qd (no dosage adjustments for elderly patients or those with renal impairment); 300 mg loading dose × 1 may be used to provide faster onset of antiplatelet effect.